Elena and her husband, Milan, were living in Russia, where they met, when they had their first daughter, Josephine. At 4 months old, the Villareals noticed something was wrong with Josephine, so they went to the pediatrician. The doctor told Elena and Milan their daughter had Spinal Muscular Atrophy Type 1 (SMA). In 2011, the Villareals decided to move to the United States, where there was more research being done for Spinal Muscular Atrophy. There is no cure for SMA and the average life expectancy is 1-2 years old. Josephine passed away at 15 months in May 2012.